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Homeotic selector genes code for DNA binding proteins (transcription factor)

-transcriptiefactor:

•         homeodomain (protein)

•         homeobox (DNA)

•         interaction with DNA and with other regulatory proteins

•         helix-turn-helix DNA binding motif

•         60 amino acids domain

•         HOX genes are a subgroup of homeobox genes

 

*Order of sequence matches the spatial order of expression

-HOX complex: chromosome region with hox genes