DO YOU
KNOW ? Most DNA is located in the cell nucleus (where
it is called nuclear DNA), but a small amount of DNA can also be found in the
mitochondria (where it is called mitochondrial DNA or mtDNA). The information in
DNA is stored as a code made up of four chemical bases: adenine (A), guanine
(G), cytosine (C), and thymine (T). Human DNA consists of about 3 billion bases,
and more than 99 percent of those bases are the same in all people. The order,
or sequence, of these bases determines the information available for building
and maintaining an organism, similar to the way in which letters of the alphabet
appear in a certain order to form words and sentences. DNA bases pair up with
each other, A with T and C with G, to form units called base pairs. Each base is
also attached to a sugar molecule and a phosphate molecule. Together, a base,
sugar, and phosphate are called a nucleotide. Nucleotides are arranged in two
long strands that form a spiral called a double helix. The structure of the
double helix is somewhat like a ladder, with the base pairs forming the ladder’s
rungs and the sugar and phosphate molecules forming the vertical sidepieces of
the ladder. An important property of DNA is that it can replicate, or make
copies of itself. Each strand of DNA in the double helix can serve as a pattern
for duplicating the sequence of bases. This is critical when cells divide
because each new cell needs to have an exact copy of the DNA present in the old
cell. DNA is a double helix formed by base pairs attached to a sugar-phosphate
backbone. For more information about DNA: For additional information about the
structure of DNA, please refer to the chapter called What Is A Genome? in the
NCBI Science Primer. Scroll down to the heading “The Physical Structure of the
Human Genome."(from wikipedia.com).